Performance information

• Identification of an antibacterial polypeptide in mouse seminal vesicle secretions　　　　　　　　　　　　　　　
  Kazunori Morohoshi; Takeo Yamazaki; Keiji Kito; Ban Sato; Woojin Kang; Taku Hibino; Manabu Yoshida; Kaoru Yoshida; Teruaki Iwamoto; Mitsutoshi Yamada; Kenji Miyado; Natsuko Kawano
  Journal of Reproductive Immunology, First page：103436, Last page：103436, Oct. 2021, [Reviewed]
  Elsevier BV, Scientific journal
  DOI：https://doi.org/10.1016/j.jri.2021.103436
  DOI ID：10.1016/j.jri.2021.103436, ISSN：0165-0378
• Development of the coelomic cavities in larvae of the living isocrinid sea lily Metacrinus rotundus
  Amemiya S; Hibino T; Minokawa T; Naruse K; Kamei Y; Uemura I; Kiyomoto M; Hisanaga S.-I; Kuraishi R
  Acta Zoologica, Volume：100, Number：4, First page：414, Last page：430, Oct. 2019, [Reviewed]
  Wiley, Scientific journal
  DOI：https://doi.org/10.1111/azo.12274
  DOI ID：10.1111/azo.12274, ISSN：0001-7272, eISSN：1463-6395, ORCID：57103730, SCOPUS ID：85053661947
• Deletion of a Seminal Gene Cluster Reinforces a Crucial Role of SVS2 in Male Fertility.　　　　　　　　　　　　　　　
  Miyuki Shindo; Masafumi Inui; Woojin Kang; Moe Tamano; Cai Tingwei; Shuji Takada; Taku Hibino; Manabu Yoshida; Kaoru Yoshida; Hiroshi Okada; Teruaki Iwamoto; Kenji Miyado; Natsuko Kawano
  International journal of molecular sciences, Volume：20, Number：18, Sep. 2019, [Reviewed], ［International magazine］
  Multiple genes, whose functions or expression are overlapping, compensate for the loss of one gene. A gene cluster in the mouse genome encodes five seminal vesicle proteins (SVS2, SVS3, SVS4, SVS5, and SVS6). These proteins are produced by male rodents and function in formation of the copulatory plug following mating. SVS2 plays an essential role in the successful internal fertilization by protecting the sperm membrane against a uterine immune attack. We hypothesized that the four remaining seminal vesicle proteins (SVPs) of this gene cluster may partially/completely compensate for the deficiency of SVS2. For confirming our hypothesis, we generated mice lacking the entire SVP-encoding gene cluster and compared their fecundity with Svs2-deficient (Svs2-/-) mice; that is, mice deficient in Svs2 alone. A single loxP site remained after the deletion of the Svs2 gene. Therefore, we inserted another loxP site by combining the CRISPR/Cas9 system with single-stranded oligodeoxynucleotides (ssODN). Male mice lacking the entire SVP-encoding gene cluster (Svs2-6-/- mice) and thereby all five SVP proteins, generated by the deletion of 100kbp genomic DNA, showed low fecundity. However, the fecundity level was comparable with that from Svs2-/- male mice. Our results demonstrate that SVS3, SVS4, SVS5, and SVS6 do not function in the protection of sperm against a uterine immune attack in the absence of SVS2. Thus, Svs2 is the critical gene in the SVP gene cluster.
  English, Scientific journal
  DOI：https://doi.org/10.3390/ijms20184557
  DOI ID：10.3390/ijms20184557, PubMed ID：31540031, PubMed Central ID：PMC6769479
• Cidaroids, clypeasteroids, and spatangoids: Procurement, culture, and basic methods
  Hibino T; Minokawa T; Yamazaki A
  Methods in Cell Biology, Volume：150, First page：81, Last page：103, Jan. 2019, [Reviewed]
  DOI：https://doi.org/10.1016/bs.mcb.2018.09.012
  DOI ID：10.1016/bs.mcb.2018.09.012, ORCID：57103723, SCOPUS ID：85056708456
• IL17 factors are early regulators in the gut epithelium during inflammatory response to Vibrio in the sea urchin larva　　　　　　　　　　　　　　　
  Katherine M. Buckley; Eric Chun Hei Ho; Taku Hibino; Catherine S. Schrankel; Nicholas W. Schuh; Guizhi Wang; Jonathan P. Rast
  ELIFE, Volume：6, Number：e23481, First page：1, Last page：24, Apr. 2017, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.7554/eLife.23481
  DOI ID：10.7554/eLife.23481, ISSN：2050-084X, ORCID：57103731, SCOPUS ID：85020441127, Web of Science ID：WOS:000402554100001
• Perturbation of gut bacteria induces a coordinated cellular immune response in the purple sea urchin larva　　　　　　　　　　　　　　　
  Eric C. H. Ho; Katherine M. Buckley; Catherine S. Schrankel; Nicholas W. Schuh; Taku Hibino; Cynthia M. Solek; Koeun Bae; Guizhi Wang; Jonathan P. Rast
  IMMUNOLOGY AND CELL BIOLOGY, Volume：94, Number：9, First page：861, Last page：874, Oct. 2016, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1038/icb.2016.51
  DOI ID：10.1038/icb.2016.51, ISSN：0818-9641, eISSN：1440-1711, ORCID：57103719, SCOPUS ID：84977068191, Web of Science ID：WOS:000386789200007
• Early stalked stages in ontogeny of the living isocrinid sea lily Metacrinus rotundus　　　　　　　　　　　　　　　
  Shonan Amemiya; Akihito Omori; Toko Tsurugaya; Taku Hibino; Masaaki Yamaguchi; Ritsu Kuraishi; Masato Kiyomoto; Takuya Minokawa
  ACTA ZOOLOGICA, Volume：97, Number：1, First page：102, Last page：116, Jan. 2016, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1111/azo.12109
  DOI ID：10.1111/azo.12109, ISSN：0001-7272, eISSN：1463-6395, ORCID：57103720, SCOPUS ID：84954392628, Web of Science ID：WOS:000368010100010
• Development ciliary bands in larvae. of the living isocrinid sea lily Metacrinus rotundus　　　　　　　　　　　　　　　
  Shonan Amemiya; Taku Hibino; Hiroaki Nakano; Masaaki Yamaguchi; Ritsu Kuraishi; Masato Kiyomoto
  ACTA ZOOLOGICA, Volume：96, Number：1, First page：37, Last page：44, Jan. 2015, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1111/azo.12049
  DOI ID：10.1111/azo.12049, ISSN：0001-7272, eISSN：1463-6395, ORCID：57103724, PubMed ID：25641974, SCOPUS ID：84919835996, Web of Science ID：WOS:000346775600004
• Seminal vesicle protein SVS2 is required for sperm survival in the uterus　　　　　　　　　　　　　　　
  Natsuko Kawano; Naoya Araki; Kaoru Yoshida; Taku Hibino; Naoko Ohnami; Maako Makino; Seiya Kanai; Hidetoshi Hasuwa; Manabu Yoshida; Kenji Miyado; Akihiro Umezawa
  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Volume：111, Number：11, First page：4145, Last page：4150, Mar. 2014, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1073/pnas.1320715111
  DOI ID：10.1073/pnas.1320715111, ISSN：0027-8424, ORCID：57103717, PubMed ID：24591616, SCOPUS ID：84896533547, Web of Science ID：WOS:000333027900061
• A novel third complement component C3 gene of Ciona intestinalis expressed in the endoderm at the early developmental stages
  T. Hibino; M. Nonaka
  ISJ-INVERTEBRATE SURVIVAL JOURNAL, Volume：10, Number：1, First page：29, Last page：37, Mar. 2013, [Reviewed], [Lead]
  English, Scientific journal
  ISSN：1824-307X, ORCID：57103711, SCOPUS ID：84925273676, Web of Science ID：WOS:000322360500004
• Sp185/333: A novel family of genes and proteins involved in the purple sea urchin immune response　　　　　　　　　　　　　　　
  Julie Ghosh; Katherine M. Buckley; Sham V. Nair; David A. Raftos; Chase Miller; Audrey J. Majeske; Taku Hibino; Jonathan P. Rast; Mattias Roth; L. Courtney Smith
  DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, Volume：34, Number：3, First page：235, Last page：245, Mar. 2010, [Reviewed]
  English
  DOI：https://doi.org/10.1016/j.dci.2009.10.008
  DOI ID：10.1016/j.dci.2009.10.008, ISSN：0145-305X, ORCID：57103728, PubMed ID：19887082, SCOPUS ID：73249143320, Web of Science ID：WOS:000274832700001
• Evolution of body axes in deuterostomes viewed from left-right asymmetry in sea urchin larvae　　　　　　　　　　　　　　　
  日比野 拓
  Cell technology., Volume：27, Number：6, First page：548, Last page：552, Jun. 2008, [Invited]
  秀潤社, Japanese
  ISSN：0287-3796, CiNii Articles ID：40016077805, CiNii Books ID：AN00069897
• Phylogenetic correspondence of the body axes in bilaterians is revealed by the right-sided expression of Pitx genes in echinoderm larvae　　　　　　　　　　　　　　　
  Taku Hibino; Atsuo Nishino; Shonan Amemiya
  DEVELOPMENT GROWTH & DIFFERENTIATION, Volume：48, Number：9, First page：587, Last page：595, Dec. 2006, [Reviewed], [Lead]
  English, Scientific journal
  DOI：https://doi.org/10.1111/j.1440-169x.2006.00892.x
  DOI ID：10.1111/j.1440-169x.2006.00892.x, ISSN：0012-1592, CiNii Articles ID：10018808295, ORCID：57103733, PubMed ID：17118013, SCOPUS ID：33750892936, Web of Science ID：WOS:000241914700004
• The immune gene repertoire encoded in the purple sea urchin genome　　　　　　　　　　　　　　　
  Taku Hibino; Mariano Loza-Coll; Cynthia Messier; Audrey J. Majeske; Avis H. Cohen; David P. Terwilliger; Katherine M. Buckley; Virginia Brockton; Sham V. Nair; Kevin Berney; Sebastian D. Fugmann; Michele K. Anderson; Zeev Pancer; R. Andrew Cameron; L. Courtney Smith; Jonathan P. Rast
  DEVELOPMENTAL BIOLOGY, Volume：300, Number：1, First page：349, Last page：365, Dec. 2006, [Reviewed], [Lead]
  English
  DOI：https://doi.org/10.1016/j.ydbio.2006.08.065
  DOI ID：10.1016/j.ydbio.2006.08.065, ISSN：0012-1606, eISSN：1095-564X, ORCID：57103721, PubMed ID：17027739, SCOPUS ID：33751549306, Web of Science ID：WOS:000242873300027
• RTK and TGF-beta signaling pathways genes in the sea urchin genome　　　　　　　　　　　　　　　
  Francois Lapraz; Eric Rottinger; Veronique Duboc; Ryan Range; Louise Duloquin; Katherine Walton; Shu-Yu Wu; Cynthia Bradham; Mariano A. Loza; Taku Hibino; Karen Wilson; Albert Poustka; Dave McClay; Lynne Angerer; Christian Gache; Thierry Lepage
  DEVELOPMENTAL BIOLOGY, Volume：300, Number：1, First page：132, Last page：152, Dec. 2006, [Reviewed]
  English
  DOI：https://doi.org/10.1016/j.ydbio.2006.08.048
  DOI ID：10.1016/j.ydbio.2006.08.048, ISSN：0012-1606, eISSN：1095-564X, CiNii Articles ID：80018716920, ORCID：57103716, PubMed ID：17084834, SCOPUS ID：33846808910, Web of Science ID：WOS:000242873300013
• Research article - The genome of the sea urchin Strongylocentrotus purpuratus　　　　　　　　　　　　　　　
  Erica Sodergren; George M. Weinstock; Eric H. Davidson; R. Andrew Cameron; Richard A. Gibbs; George M. Weinstock; Robert C. Angerer; Lynne M. Angerer; Maria Ina Arnone; David R. Burgess; Robert D. Burke; R. Andrew Cameron; James A. Coffman; Eric H. Davidson; Michael Dean; Maurice R. Elphick; Charles A. Ettensohn; Kathy R. Foltz; Amro Hamdoun; Richard O. Hynes; William H. Klein; William Marzluff; David R. McClay; Robert L. Morris; Arcady Mushegian; Jonathan P. Rast; Erica Sodergren; L. Courtney Smith; Michael C. Thorndyke; Victor D. Vacquier; George M. Weinstock; Gary M. Wessel; Greg Wray; Lan Zhang; Erica Sodergren; George M. Weinstock; Robert C. Angerer; Lynne M. Angerer; R. Andrew Cameron; Eric H. Davidson; Christine G. Elsik; Olga Ermolaeva; Wratko Hlavina; Gretchen Hofmann; Paul Kitts; Melissa J. Landrum; Aaron J. Mackey; Donna Maglott; Georgia Panopoulou; Albert J. Poustka; Kim Pruitt; Victor Sapojnikov; Xingzhi Song; Alexandre Souvorov; Victor Solovyev; Zheng Wei; Charles A. Whittaker; Kim Worley; Lan Zhang; Erica Sodergren; George M. Weinstock; K. James Durbin; Richard A. Gibbs; Yufeng Shen; Xingzhi Song; Kim Worley; Lan Zhang; Greg Wray; Olivier Fedrigo; David Garfield; Ralph Haygood; Alexander Primus; Rahul Satija; Tonya Severson; Lan Zhang; Erica Sodergren; George M. Weinstock; Manuel L. Gonzalez-Garay; Andrew R. Jackson; Aleksandar Milosavljevic; Xingzhi Song; Mark Tong; Kim Worley; Charles A. Ettensohn; R. Andrew Cameron; Christopher E. Killian; Melissa J. Landrum; Brian T. Livingston; Fred H. Wilt; James A. Coffman; William Marzluff; Arcady Mushegian; Nikki Adams; Robert Belle; Seth Carbonneau; Rocky Cheung; Patrick Cormier; Bertrand Cosson; Jenifer Croce; Antonio Fernandez-Guerra; Anne-Marie Geneviere; Manisha Goel; Hemant Kelkar; Julia Morales; Odile Mulner-Lorillon; Anthony J. Robertson; Amro Hamdoun; Jared V. Goldstone; Nikki Adams; Bryan Cole; Michael Dean; David Epel; Bert Gold; Mark E. Hahn; Meredith Howard-Ashby; Mark Scally; John J. Stegeman; Robert L. Morris; Erin L. Allgood; Jonah Cool; Kyle M. Judkins; Shawn S. McCafferty; Ashlan M. Musante; Robert A. Obar; Amanda P. Rawson; Blair J. Rossetti; David R. Burgess; Erin L. Allgood; Jonah Cool; Ian R. Gibbons; Matthew P. Hoffman; Kyle M. Judkins; Andrew Leone; Shawn S. McCafferty; Robert L. Morris; Ashlan M. Musante; Robert A. Obar; Amanda P. Rawson; Blair J. Rossetti; Gary M. Wessel; Eric H. Davidson; R. Andrew Cameron; Sorin Istrail; Stefan C. Materna; Manoj P. Samanta; Viktor Stolc; Waraporn Tongprasit; Qiang Tu; Robert C. Angerer; Lynne M. Angerer; Zheng Wei; Richard O. Hynes; Karl-Frederik Bergeron; Bruce P. Brandhorst; Robert D. Burke; Charles A. Whittaker; James Whittle; R. Andrew Cameron; Kevin Berney; David J. Bottjer; Cristina Calestani; Eric H. Davidson; Kevin Peterson; Elly Chow; Qiu Autumn Yuan; Eran Elhaik; Christine G. Elsik; Dan Graur; Justin T. Reese; Ian Bosdet; Shin Heesun; Marco A. Marra; Jacqueline Schein; Michael Dean; Amro Hamdoun; Jonathan P. Rast; L. Courtney Smith; Michele K. Anderson; Kevin Berney; Virginia Brockton; Katherine M. Buckley; R. Andrew Cameron; Avis H. Cohen; Sebastian D. Fugmann; Taku Hibino; Mariano Loza-Coll; Audrey J. Majeske; Cynthia Messier; Sham V. Nair; Zeev Pancer; David P. Terwilliger; Robert D. Burke; Maurice R. Elphick; William H. Klein; Michael C. Thorndyke; Cavit Agca; Lynne M. Angerer; Enrique Arboleda; Maria Ina Arnone; Bruce P. Brandhorst; Nansheng Chen; Allison M. Churcher; F. Hallboeoek; Glen W. Humphrey; Richard O. Hynes; Mohammed M. Idris; Takae Kiyama; Shuguang Liang; Dan Mellott; Xiuqian Mu; Greg Murray; Robert P. Olinski; Florian Raible; Matthew Rowe; John S. Taylor; Kristin Tessmar-Raible; D. Wang; Karen H. Wilson; Shunsuke Yaguchi; Kathy R. Foltz; Victor D. Vacquier; Gary M. Wessel; Terry Gaasterland; Blanca E. Galindo; Herath J. Gunaratne; Meredith Howard-Ashby; Glen W. Humphrey; Celina Juliano; Masashi Kinukawa; Gary W. Moy; Anna T. Neill; Mamoru Nomura; Michael Raisch; Anna Reade; Michelle M. Roux; Jia L. Song; Yi-Hsien Su; Ian K. Townley; Ekaterina Voronina; Julian L. Wong; Maria Ina Arnone; Michael C. Thorndyke; Gabriele Amore; Lynne M. Angerer; Enrique Arboleda; Margherita Branno; Euan R. Brown; Vincenzo Cavalieri; Veronique Duboc; Louise Duloquin; Maurice R. Elphick; Constantin Flytzanis; Christian Gache; Anne-Marie Geneviere; Mohammed M. Idris; Francois Lapraz; Thierry Lepage; Annamaria Locascio; Pedro Martinez; Giorgio Matassi; Valeria Matranga; David R. McClay; Julia Morales; Albert J. Poustka; Florian Raible; Ryan Range; Francesca Rizzo; Eric Roettinger; Matthew Rowe; Kristin Tessmar-Raible; Erica Sodergren; George M. Weinstock; Karen Wilson; David R. McClay; Lynne M. Angerer; Maria Ina Arnone; Wendy Beane; Cynthia Bradham; Christine Byrum; Jenifer Croce; Veronique Duboc; Louise Duloquin; Christian Gache; Anne-Marie Geneviere; Tom Glenn; Taku Hibino; Sofia Hussain; Francois Lapraz; Thierry Lepage; Brian T. Livingston; Mariano Loza; Gerard Manning; Esther Miranda; Ryan Range; Francesca Rizzo; Eric Roettinger; Rebecca Thomason; Katherine Walton; Zheng Wei; Gary M. Wessel; Athula Wikramanayke; Karen H. Wilson; Charles Whittaker; Shu-Yu Wu; Ronghui Xu; Eric H. Davidson; Maria Ina Arnone; Margherita Branno; C. Titus Brown; R. Andrew Cameron; Lili Chen; Rachel F. Gray; Meredith Howard-Ashby; Sorin Istrail; Pei Yun Lee; Annamaria Locascio; Pedro Martinez; Stefan C. Materna; Jongmin Nam; Paola Oliveri; Francesca Rizzo; Joel Smith; Donna Muzny; Erica Sodergren; Richard A. Gibbs; George M. Weinstock; Stephanie Bell; Joseph Chacko; Andrew Cree; Stacey Curry; Clay Davis; Huyen Dinh; Shannon Dugan-Rocha; Jerry Fowler; Rachel Gill; Cerrissa Hamilton; Judith Hernandez; Sandra Hines; Jennifer Hume; LaRonda Jackson; Angela Jolivet; Christie Kovar; Sandra Lee; Lora Lewis; George Miner; Margaret Morgan; Lynne V. Nazareth; Geoffrey Okwuonu; David Parker; Ling-Ling Pu; Yufeng Shen; Rachel Thom; Rita Wright
  SCIENCE, Volume：314, Number：5801, First page：941, Last page：952, Nov. 2006, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1126/science.1133609
  DOI ID：10.1126/science.1133609, ISSN：0036-8075, CiNii Articles ID：30020565990, ORCID：57103713, PubMed ID：17095691, SCOPUS ID：33750995860, Web of Science ID：WOS:000241896000039
• Review - Genomic insights into the immune system of the sea urchin　　　　　　　　　　　　　　　
  Jonathan P. Rast; L. Courtney Smith; Mariano Loza-Coll; Taku Hibino; Gary W. Litman
  SCIENCE, Volume：314, Number：5801, First page：952, Last page：956, Nov. 2006, [Reviewed]
  English
  DOI：https://doi.org/10.1126/science.1134301
  DOI ID：10.1126/science.1134301, ISSN：0036-8075, CiNii Articles ID：80018776789, ORCID：57103725, PubMed ID：17095692, SCOPUS ID：33750980112, Web of Science ID：WOS:000241896000040
• Ion flow regulates left-right asymmetry in sea urchin development　　　　　　　　　　　　　　　
  T Hibino; Y Ishii; M Levin; A Nishino
  DEVELOPMENT GENES AND EVOLUTION, Volume：216, Number：5, First page：265, Last page：276, May 2006, [Reviewed], [Lead]
  English, Scientific journal
  DOI：https://doi.org/10.1007/s00427-005-0051-6
  DOI ID：10.1007/s00427-005-0051-6, ISSN：0949-944X, CiNii Articles ID：10024443340, ORCID：57103722, PubMed ID：16534626, SCOPUS ID：33645870420, Web of Science ID：WOS:000236967500004
• Molecular heterotopy in the expression of Brachyury orthologs in order Clypeasteroida (irregular sea urchins) and order Echinoida (regular sea urchins)　　　　　　　　　　　　　　　
  T Hibino; Y Harada; T Minokawa; M Nonaka; S Amemiya
  DEVELOPMENT GENES AND EVOLUTION, Volume：214, Number：11, First page：546, Last page：558, Nov. 2004, [Reviewed], [Lead]
  English, Scientific journal
  DOI：https://doi.org/10.1007/s00427-004-0437-x
  DOI ID：10.1007/s00427-004-0437-x, ISSN：0949-944X, ORCID：57103715, SCOPUS ID：8544284103, Web of Science ID：WOS:000224954800003
• Regrowth of the stalk of the sea lily, Metacrinus rotundus (Echinodermata : crinoidea)　　　　　　　　　　　　　　　
  H Nakano; T Hibino; Y Hara; T Oji; S Amemiya
  JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-COMPARATIVE EXPERIMENTAL BIOLOGY, Volume：301A, Number：6, First page：464, Last page：471, Jun. 2004, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1002/jez.a.77
  DOI ID：10.1002/jez.a.77, ISSN：0022-104X, ORCID：57103729, SCOPUS ID：3042850763, Web of Science ID：WOS:000221985500002
• Development of the sea lily Metacrinus rotundus: Comparisons with feather stars　　　　　　　　　　　　　　　
  Nakano H; Hibino T; Hara Y; Oji T; Amemiya S
  Proceedings of the 11th International Echinoderm Conference, First page：41-44, Jan. 2004, [Reviewed]
  English, International conference proceedings
• Larval stages of a living sea lily (stalked crinoid echinoderm)　　　　　　　　　　　　　　　
  H Nakano; T Hibino; T Oji; Y Hara; S Amemiya
  NATURE, Volume：421, Number：6919, First page：158, Last page：160, Jan. 2003, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1038/nature01236
  DOI ID：10.1038/nature01236, ISSN：0028-0836, CiNii Articles ID：80015736591, ORCID：57103726, PubMed ID：12520300, SCOPUS ID：0346634891, Web of Science ID：WOS:000180267200038
• The behavior and the morphology of sea lilies with shortened stalks: Implications on the evolution of feather stars　　　　　　　　　　　　　　　
  H Nakano; T Hibino; Y Hara; T Oji; S Amemiya
  ZOOLOGICAL SCIENCE, Volume：19, Number：8, First page：961, Last page：964, Aug. 2002, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.2108/zsj.19.961
  DOI ID：10.2108/zsj.19.961, ISSN：0289-0003, CiNii Articles ID：110003372800, ORCID：57103714, PubMed ID：12193811, SCOPUS ID：0036703130, Web of Science ID：WOS:000179250500014
• The centrosome-attracting body, microtubule system, and posterior egg cytoplasm are involved in positioning of cleavage planes in the ascidian embryo　　　　　　　　　　　　　　　
  T Nishikata; T Hibino; H Nishida
  DEVELOPMENTAL BIOLOGY, Volume：209, Number：1, First page：72, Last page：85, May 1999, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1006/dbio.1999.9244
  DOI ID：10.1006/dbio.1999.9244, ISSN：0012-1606, CiNii Articles ID：80011048021, ORCID：57103727, PubMed ID：10208744, SCOPUS ID：0033135884, Web of Science ID：WOS:000079924400007
• Centrosome-attracting body: A novel structure closely related to unequal cleavages in the ascidian embryo　　　　　　　　　　　　　　　
  T Hibino; T Nishikata; H Nishida
  DEVELOPMENT GROWTH & DIFFERENTIATION, Volume：40, Number：1, First page：85, Last page：95, Feb. 1998, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1046/j.1440-169X.1998.t01-5-00010.x
  DOI ID：10.1046/j.1440-169X.1998.t01-5-00010.x, ISSN：0012-1592, ORCID：57103732, SCOPUS ID：0031943947, Web of Science ID：WOS:000072500000010

• Aquatic Fauna of Hozoji Pond Surveyed Using Environmental DNA Analyses : Compared to Field Surveys　　　　　　　　　　　　　　　
  吉田 竜矢; 日比野 拓
  埼玉大学紀要. 教育学部 = Journal of Saitama University. Faculty of Education, Volume：68, Number：1, First page：317, Last page：331, 2019
  Faculty of Education, Saitama University, Japanese
  ISSN：1881-5146, CiNii Articles ID：120006585307
• Four Years of Change in Aquatic Fauna in Hozoji Pond After the Emergency Research for Saving the Endangered Aquatic Plant, Aldrovanda vesiculosa L.　　　　　　　　　　　　　　　
  吉田 竜矢; 宇田川 貴大; 日比野 拓
  埼玉大学紀要. 教育学部 = Journal of Saitama University. Faculty of Education, Volume：67, Number：2, First page：341, Last page：351, 2018
  Faculty of Education, Saitama University, Japanese
  ISSN：1881-5146, CiNii Articles ID：120006533500
• 私の実験動物＃５ タコノマクラ　　　　　　　　　　　　　　　
  日比野 拓
  Volume：49, First page：20, Last page：23, 2018
• Development of immune card games for teaching materials　　　　　　　　　　　　　　　
  HIBINO Taku
  JADCI News, Volume：46, First page：5, Last page：6, Jun. 2017
  Japanese
• Developing an Environmental Education Program Closely Related to a Local Community : Presenting Data on Aquatic Fauna in Hozoji Pond, a Natural Habitat of Aldrovanda vesiculosa L.　　　　　　　　　　　　　　　
  吉田 竜矢; 田端 雄樹; 伊藤 悠昭; 山本 孔紀; 矢辺 徹; 金子 康子; 日比野 拓
  埼玉大学紀要. 教育学部 = Journal of Saitama University. Faculty of Education, Volume：66, Number：2, First page：609, Last page：622, 2017
  Faculty of Education, Saitama University, Japanese
  ISSN：1881-5146, CiNii Articles ID：120006389474
• TLR Card Game : Developed for Understanding Pathogen Recognition by the Innate Immune System　　　　　　　　　　　　　　　
  日比野 拓
  埼玉大学紀要. 教育学部, Volume：65, Number：2, First page：261, Last page：270, Oct. 2016
  Toll-like receptors (TLRs) are protein sensors located on immune cells, which function as pathogen recognition by the innate immune system. These TLRs form a homodimer or a heterodimer, which recognizes distinct pathogen-associated molecular patterns. The explanation of the TLRs and their function have been introduced on Japanese biological textbooks for high school students since 2012. Here, I developed a card game, TLR Card Game, as an educational material for understanding the mechanism of the innate pathogen recognition. The TLR Card Game is for multiplayers who are surrounding a table where several pairs of a phagocytic cell board and a pathogen card are set. Each player has to present two TLR cards from his own hand in his turn, making a TLR dimer corresponding to a pathogen card presenting on the table. When a TLR card-pair is presented correctly, a player can get several points, and the player with highest points finally gets win. The TLR Card Game was carried out in an extracurricular class of a high school in Saitama City. The effectiveness of the game was assessed by open- and close-ended questionnaires for 30 students. All the students got interested in the TLR Card Game and its immunology. Some students, however, answered that the game and the immune mechanism were not much linked in their thought. The TLR Card Game is considered useful for students attracted towards immunology, but the instructions before use needed to be improved.
  埼玉大学教育学部, Japanese
  ISSN：1881-5146, CiNii Articles ID：120005853513
• 実験・観察の活動を取り入れた生活科授業―教科内容学模索の取り組み―　　　　　　　　　　　　　　　
  鶴ヶ谷柊子; 日比野拓
  埼玉大学教育学部附属教育実践総合センター紀要, Number：15, First page：135‐140, Last page：140, 26 Feb. 2016
  近年、教科専門と教科教育を架橋する分野として「教科内容学」の研究が進んでいる。小学校低学年の教科である生活科は「具体的な活動や体験」を通した学びが重視されている。本研究では、教科内容学の視点から、生活科の講義における、実験・観察の活動の導入と学生の生活科に対する理解の関連について実践と検討を行った。その結果、具体的な活動を講義に取り入れることは有効であるが、受講者の持つ知識に応じて、実験・観察の活動内容を組み立てることが、生活科の特徴への理解を深める上でも必要であることがわかった。
  Japanese
  ISSN：1347-7420, J-Global ID：201702290329001002, CiNii Articles ID：120005818438, CiNii Books ID：AA11948173
• ムジナモ保全のための遺伝的多様性の解析　　　　　　　　　　　　　　　
  日比野 拓; 川合 真紀
  First page：72, Last page：81, 2015
  Japanese
• 水生動物相の変遷とムジナモ食害の調査　　　　　　　　　　　　　　　
  日比野 拓; 宇田川 貴大; 伊藤 悠昭; 矢辺 徹; 梅沢 一弘; 関森 清己
  First page：82, Last page：96, 2015
  Japanese
• ウニ幼生における貪食作用に関わる細胞の同定　　　　　　　　　　　　　　　
  日比野 拓
  Volume：7, 2009
  Japanese
• ウニ幼生の左右非対称性から後口動物の体軸の進化を考える　　　　　　　　　　　　　　　
  日比野 拓
  Volume：21, First page：1, Last page：4, 2009
  Japanese, Introduction other
• CHANGES IN THE MORPHOLOGY OF SEA LILIES WITH SHORTENED STALKS(Taxonomy and Systematics)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan) :　　　　　　　　　　　　　　　
  Nakano Hiroaki; Hibino Taku; Hara Yuko; Oji Tatsuo; Amemiya Shonan
  Zoological science, Volume：19, Number：12, First page：1425, Last page：1425, 2002
  Zoological Society of Japan, English
  ISSN：0289-0003, CiNii Articles ID：110003376235, CiNii Books ID：AA10545874
• DEVELOPMENT OF THE STALKED CRINOID, METACRINUS ROTUNDUS(Developmental Biology)(Proceeding of the Seventy-Third Annual Meeting of the Zoological Society of Japan) :　　　　　　　　　　　　　　　
  Nakano Hiroaki; Hara Yuko; Oji Tatsuo; Amemiya Shonan; Hibino Taku
  Zoological science, Volume：18, First page：79, Last page：79, 2001
  Zoological Society of Japan, English
  ISSN：0289-0003, CiNii Articles ID：110003372443, CiNii Books ID：AA10545874

• ぼくらは「生物学」のおかげで生きている (素晴らしきサイエンス)　　　　　　　　　　　　　　　
  金子康子; 日比野拓, [Joint work]
  Dec. 2015
  Total pages：232
  

  

  
  ISBN：4788911701, ASIN：4788911701, EAN：9784788911703

• THE SOCIETY OF BIOLOGICAL SCIENCES EDUCATION OF JAPAN

• 科学と人間生活との関わりを理解し生きる力を育む教材開発　　　　　　　　　　　　　　　
  01 Apr. 2021 - 31 Mar. 2024
  Grant amount(Total)：3380000, Direct funding：2600000, Indirect funding：780000
  Grant number：21K02898
• Study on the post-embryonic development of the echinoids　　　　　　　　　　　　　　　
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), 01 Apr. 2018 - 31 Mar. 2021
  Minokawa Takuya, Tohoku University
  Grant amount(Total)：4420000, Direct funding：3400000, Indirect funding：1020000
  The present study deals the questions related to post-embryonic development, such as what is a larva, what is an adult, and what is the mechanism that forms an adult. We focus on the following two topics: [1] Formation process and structure of adult rudiment in normal echinoid development, and [2] Understanding the mechanical relationship between embryonic and post-embryonic development using the regeneration experimental system. For [1], We have discovered a new feature in the morphological change of the digestive tract during the metamorphosis period from larva to adult. Regarding [2], it was verified whether or not the larval constituent cells are involved in post-embryonic development using a larval regeneration experimental system. It was confirmed that the larvae can regenerate the missing part and reconstruct the functionally and structurally normal digestive tract even if most of the digestive tract is removed experimentally.
  Grant number：18K06307
• 免疫システムと社会をつなぐ教材の開発と普及　　　　　　　　　　　　　　　
  Apr. 2017 - Mar. 2020
  Principal investigator
  Competitive research funding
• Development of educational materials to assist students with understanding cellular and molecular immunity　　　　　　　　　　　　　　　
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Apr. 2014 - Mar. 2017
  HIBINO Taku, Saitama University, Principal investigator
  Grant amount(Total)：4810000, Direct funding：3700000, Indirect funding：1110000
  Toll-like receptors (TLRs) are protein sensors located on immune cells, which function as pathogen recognition by the innate immune system. I developed TLR Card Game as an educational material to assist students with understanding the mechanism of the innate pathogen recognition. The TLR Card Game was carried out in an extracurricular class of a high school in Saitama City. The effectiveness of the material was assessed by questionnaires for 30 students. All the students got interested in the game and its immunology. Next, I developed An Adventure to Comprehend Immunity, which is a board game for connecting a desktop learning of immunology with an everyday occurrence and the world. Finally, the embryos of three echinoids were tested if they are suitable to observe in vivo phagocytosis. A swift phagocytosis was occurred in the blastocoel of the embryo of Clypeaster japonicus, thus this species is better for educational experiment.
  Competitive research funding, Grant number：26350225
• Molecular evolution of ancient TIR containing gene family in innate immunity　　　　　　　　　　　　　　　
  JSPS, Grants-in-Aid for Scientific Research(若手研究(B)), 若手研究(B), Apr. 2010 - Mar. 2012
  Taku HIBINO, 埼玉大学, Principal investigator
  Grant amount(Total)：4290000, Direct funding：3300000, Indirect funding：990000
  To unveil a repertoire of Toll-like receptors (TLRs) and TIR containing signaling molecules in a basal deuterostome, we analyzed EST of a stalked crinoid, Metacrinus rotundas, whose embryonic and larval cDNA have been sequenced by Next Gene Sequencing. So far, we identified 6 TLRs that consist of 3 genes of fly-type and 3 genes of vertebrate type TLRs. MyD88-like genes and Sarm-like genes were also identified in the cDNA of the sea lily, suggesting these genes exist in a basal deuterostome. We found unique TIR containing gene families, CARD-TIR and TPR-TIR, in the sequencing data of the sea lily, which have not been in the genome of the sea urchin, but in that of amphioxus. These data suggest a basal deuterostome could utilize multigenes of TLRs and various types of TIR containing genes. And the refinement of TLRs and signaling molecules could happen after the appearance of acquired immunity.
  Competitive research funding, Grant number：22770232
• A project which gives surprise and impression and makes science favorite in order to prevent dislike of science.　　　　　　　　　　　　　　　
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), 2009 - 2012
  ASHIDA Minoru; OHMUKAI Ryuzo; HIBINO Taku; OKAMOTO Kazuaki; SHIMIZU Makoto; KATAHIRA Katsuhiro; YATSUKA Mitsunori; ASHIDA Masami, Saitama University
  Grant amount(Total)：19240000, Direct funding：14800000, Indirect funding：4440000
  Various enterprises were undertaken in order to prevent dislike of science. The students were dispatched to elementary schools as a helper. They were engaged in arrangement of a science laboratory and assistance of a lesson. The students were dispatched to the event of a science museum, the studying classroom in Misato, the contact enterprise of Kawagoe, etc. In the observation experiment classroom, we gave children various surprise and impression at elementary schools, etc. Moreover, astronomical observation meetings and workshops were held. We replied to many questions by the homepage and exhibited how to make solutions, simulation of experiments and science calendars.
  Grant number：21300288
• Molecular evolution of multiplicity of Toll-like receptors in echinoderm genome　　　　　　　　　　　　　　　
  JSPS, Grants-in-Aid for Scientific Research(若手研究(スタートアップ)), 若手研究(スタートアップ), Apr. 2008 - Mar. 2010
  Taku HIBINO, 埼玉大学, Principal investigator
  Grant amount(Total)：3302000, Direct funding：2540000, Indirect funding：762000
  It has been known that approximately 10 Toll-like receptors (TLRs) in the genome of fruit fly and human. On the other hand the genomes of marine invertebrates such as a sea urchin, an amphioxus and a polychaete contain approximately 70 to 200 TLRs forming multigene family. We investigated molecular evolution of TLRs and innate immune related genes between human and fruit fly, and marine invertebrates. Multiplication of IL-17 and Sarm-like gene family that contains an old-TIR domain were found uniquely in these marine invertebrates. Appearance of these gene families may be related to multiplicity of TLRs.
  Competitive research funding, Grant number：20870007
• 免疫細胞分化の遺伝子制御ネットワーク解析　　　　　　　　　　　　　　　
  Apr. 2005 - Mar. 2006
  Principal investigator
  Competitive research funding
• -　　　　　　　　　　　　　　　
  Competitive research funding

• ひらめき☆ときめきサイエンス～ようこそ大学の研究室へ～KAKENHI「ウニを使った観察実験で＜受精＞と＜免疫＞の理解を深めよう」　　　　　　　　　　　　　　　
  lecturer, planner
  Jul. 2019
• ひらめき☆ときめきサイエンス～ようこそ大学の研究室へ～KAKENHI「透明なウニを使って生命のはじまりと細胞の動きを観察しよう」　　　　　　　　　　　　　　　
  lecturer, planner
  Jul. 2018
• ひらめき☆ときめきサイエンス～ようこそ大学の研究室へ～KAKENHI「ウニはどのように発生し、侵入する細菌から身を守るのでしょう？」　　　　　　　　　　　　　　　
  lecturer, planner
  Jul. 2016